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Saudi Just Approved Its First-Ever Alzheimer’s Drug And It’s A Big Deal For Regional Healthcare
The Saudi Food and Drug Authority (SFDA) has officially approved Leqembi (lecanemab), a breakthrough treatment for early-stage Alzheimer’s disease. The green light came on July 29, 2025, making this the first Alzheimer’s drug ever approved in the Kingdom – and it’s more than just a regulatory move, it’s a game-changer for patients and science alike.
particularly those who have mild cognitive impairment or early Alzheimer’s-type dementia. It specifically targets amyloid-beta plaques in the brain—those sticky clumps linked to memory loss and cognitive decline. Leqembi is given through IV infusion every two weeks, and studies have shown it can slow cognitive decline when used early. But it’s not for everyone—patients must undergo genetic testing to determine if they have zero or one copy of the ApoE4 gene, which affects both the drug’s effectiveness and risk profile.
With potential side effects like headaches, infusion reactions, and ARIA (abnormal changes seen on MRI scans), the SFDA isn’t taking any risks. Ongoing safety monitoring and a risk management plan are mandatory, ensuring patient safety stays front and center.
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